Hip Dysplasia is a polygenetic disease, one that is caused by several genes, with an environmental influence. Thus some dogs that are predisposed to the disease by their genes will not develop it if the environmental factors are missing from their lives.
The hip joint is a ball and socket arrangement in which the femoral head (the ball) of the thigh bone (the femur) fits into the acetabulum (the socket) of the pelvic structure. The assembly is held in place by ligaments and muscles. Malformation of either the femoral head or the acetabulum, laxity in the ligaments, and poor muscle condition all contribute to the pain and ultimate arthritis of the disease.

• http://www.offa.org/
   

Sebaceous Adenitis (SA) is a hereditary skin disease in which the sebaceous glands become inflamed, often leading to progressive loss of hair. The disease is primarily seen in Standard Poodles, Akitas, and Samoyeds, although there have been reported cases in a number of other breeds and mixed breeds as well.

Diagnosing SA can be difficult as the symptoms vary by breed, the symptoms are similar to those of other diseases such as hypothyroidism or allergies, and the disease can vary greatly in its severity. Visible symptoms include excessive dandruff or scaling, hair loss, lesions, a musty odor, and even secondary skin infections. On the other hand, dogs affected with SA can be subclinical and show no outward signs of the disease. As a result, diagnosis requires microscopic examination of tissue samples.

• http://www.poodleclubofamerica.org/healthsa.htm
   

• http://www.vipoodle.org/undst_sa.htm

Von Willebrand's disease (vWD) is a common, usually mild, inherited bleeding disorder in people and in dogs. It is caused by a lack of von Willebrand factor (vWF), which plays an essential role in the blood clotting process.

Many dogs with VWD never show outward evidence of having the disease.  Others may hemorrhage from the nose, vagina, or urinary bladder or oral mucous membranes; prolonged bleeding after trauma or surgery is common.  Females may bleed excessively after giving birth.  In affected dogs with uncontrolled hemorrhage, death may occur.

• http://www.pethealthcare.net/html/body_canine_von_willebrand_s_diseas.html
   
• http://www.vetgen.com/

Canine bloat occurs when there is gas production in the stomach and that gas buildup is unable to be expelled via belching or vomiting, or passed through the intestines and out of the dog as flatulence.  Some bloat cases occur very rapidly when fermentation of grains in the wet and warm stomach environment create gas.  The influence of grain in creating an environment conducive to bloat seems even more plausible in that it is very rare for dogs that consume meat-based diets to develop bloat.  Generally, bloat is the extreme dilation of the stomach as a result of gas buildup that cannot escape the stomach.

GASTRIC DILATATION... is simply the expansion of the stomach due to the buildup of gas or material in the stomach.
GASTRIC VOLVULUS (TORSION)... is the condition where the stomach rotates (flips on its long axis) and thereby twists the esophagus and small intestine closed so there is no passage of stomach contents or gas in or out of the stomach.

• http://www.animalclinic.com/bloat.htm
   
• http://www.thepetcenter.com/sur/bloat.html

Juvenile renal disease (JRD) and other congenital or familial forms of renal dysplasia are seen in about twenty breeds of dogs. According to Kenneth Bovee, DVM, (Professor of Medicine at the University of Pennsylvania), the clinical entity has considerable variation from breed to breed and has completely different prevalence rates. A table which lists all of the congenital and familial renal diseases of dogs by breed can be found in Veterinary Pediatrics Dogs & Cats from Birth to Six Months

• http://www.geocities.com/Heartland/Hills/9709/jrdsusanfleisher.html

Progressive retinal degeneration (PRD) is also known as progressive retinal atrophy (PRA) and refers to retinal diseases that cause blindness.

• http://www.netpets.com/dogs/healthspa/pra.html

Addison's disease is also called Hypoadrenocorticism. It results from the failure of the adrenal glands, usually due to the immune-mediated destruction of the adrenal glands. Most literature lists it as a disease that most commonly affects female dogs aged 3-5, but in SP's it strikes both males and females almost equally and at any age including puppies.

• http://www.k9addisons.com/